<i>O</i> -2-Alkylated Cytosine Acyclic Nucleoside Phosphonamidate Prodrugs Display Pan-Genotype Antiviral Activity against African Swine Fever Virus-Reference-Cited by-同舟云学术

O -2-Alkylated Cytosine Acyclic Nucleoside Phosphonamidate Prodrugs Display Pan-Genotype Antiviral Activity against African Swine Fever Virus

Published:2022-12-21 Issue:6 Volume:7 Page:
ISSN:2379-5042
Container-title:mSphere
language:en
Short-container-title:mSphere

Author:

Goulding Leah V.¹^ORCID,Kiss Eleonóra²,Vrancken Robert²,Goris Nesya²,Luo Min³,Groaz Elisabetta³,Herdewijn Piet³,Dixon Linda¹^ORCID

Affiliation:

1. The Pirbright Institute, Pirbright, Woking, United Kingdom

2. ViroVet NV, Leuven, Belgium

3. KU Leuven, Rega Institute for Medical Research, Medicinal Chemistry, Leuven, Belgium

Abstract

African swine fever virus is a highly contagious hemorrhagic viral disease. Since its transcontinental spread to Georgia in 2007, ASFV has continued to spread across the globe into countries previously without infection.

Funder

UKRI | Biotechnology and Biological Sciences Research Council

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/msphere.00378-22

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