Molecular Characteristics of IS 1216 Carrying Multidrug Resistance Gene Cluster in Serotype III/Sequence Type 19 Group B Streptococcus

Author:

Zhi Yong12,Ji Hyun Jung13,Jung Jong Hyun12,Byun Eui Baek1,Kim Woo Sik14,Lin Shun Mei1,Lim Sangyong12,Jang A-Yeung5,Choi Min Joo5,Ahn Ki Bum1,Lim Jae Hyang67,Song Joon Young5,Seo Ho Seong12ORCID

Affiliation:

1. Research Division for Biotechnology, Korea Atomic Energy Research Institute, Jeongeup, Republic of Korea

2. Department of Radiation Science, University of Science and Technology, Daejeon, Republic of Korea

3. Department of Oral Microbiology and Immunology, DRI, and BK21 Plus Program, School of Dentistry, Seoul National University, Seoul, Republic of Korea

4. Functional Biomaterial Research Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, Republic of Korea

5. Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea

6. Department of Microbiology, Ewha Womans University College of Medicine, Seoul, Republic of Korea

7. Ewha Education & Research Center for Infection, Ewha Womans University Medical Center, Seoul, Republic of Korea

Abstract

Most previously isolated group B streptococcus (GBS) strains express either the Srr1 or Srr2 glycoprotein, which plays an important role in bacterial colonization and invasion. These glycoproteins are potential protein vaccine candidates.

Funder

Ministry of Food and Drug Safety

National Research Foundation of Korea

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference76 articles.

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4. Centers for Disease Control and Prevention. 2016. Group B Streptococcus (GBS) 2016. Centers for Disease Control and Prevention, Atlanta, GA. https://www.cdc.gov/groupbstrep/index.html. Accessed 1 November 2017.

5. Progress toward a group B streptococcal vaccine

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