Molecular Evolution of Human Coronavirus 229E in Hong Kong and a Fatal COVID-19 Case Involving Coinfection with a Novel Human Coronavirus 229E Genogroup-Reference-Cited by-全球学者库

Molecular Evolution of Human Coronavirus 229E in Hong Kong and a Fatal COVID-19 Case Involving Coinfection with a Novel Human Coronavirus 229E Genogroup

Published:2021-02-24 Issue:1 Volume:6 Page:
ISSN:2379-5042
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language:en
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Author:

Lau Susanna K. P.¹²^ORCID,Lung David C.³,Wong Emily Y. M.¹,Aw-Yong Kam Leng¹^ORCID,Wong Antonio C. P.¹^ORCID,Luk Hayes K. H.¹^ORCID,Li Kenneth S. M.¹^ORCID,Fung Joshua¹^ORCID,Chan Tony T. Y.¹,Tang James Y. M.¹^ORCID,Zhu Longchao¹,Yip Cyril C. Y.¹^ORCID,Wong Sally C. Y.³,Lee Rodney A.⁴,Tsang Owen T. Y.⁵,Yuen Kwok-Yung¹²^ORCID,Woo Patrick C. Y.¹²^ORCID

Affiliation:

1. Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China

2. Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China

3. Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China

4. Department of Pathology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China

5. Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, China

Abstract

Since its first appearance in the 1960s, the genetic diversity and evolution of human coronavirus 229E (HCoV-229E) have been relatively understudied. In this study, we report a fatal case of COVID-19 coinfected with HCoV-229E in Hong Kong.

Funder

Theme-Based Research Scheme

University Development Fund

Consultancy Service for Enhancing Laboratory Surveillance of Emerging Infectious Disease for the HKSAR Department of Health

FHB | Health and Medical Research Fund

Innovation and Technology Fund

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mSphere.00819-20