Bifidobacterium longum R0175 Protects Rats against d -Galactosamine-Induced Acute Liver Failure

Author:

Wang Kaicen123,Lv Longxian123,Yan Ren123,Wang Qiangqiang123,Jiang Huiyong123,Wu Wenrui123,Li Yating123,Ye Jianzhong123,Wu Jingjing123,Yang Liya123,Bian Xiaoyuan123,Jiang Xianwan123,Lu Yanmeng123,Xie Jiaojiao123,Wang Qing123,Shen Jian123,Li Lanjuan123

Affiliation:

1. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China

2. National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China

3. Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China

Abstract

Our research investigated the protective and preventive roles of B. longum R0175 in a rat model of acute liver failure. The results illustrated that this probiotic strain exhibited protective effects in rats with acute liver failure. Thus, B. longum R0175 showed clinical application prospects that required further exploration.

Funder

Natural Science Foundation of Zhejiang Province

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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