Purification and characterization of a calicivirus as the causative agent of a lethal hemorrhagic disease in rabbits

Author:

Parra F1,Prieto M1

Affiliation:

1. Departamento de Biología Funcional (Area de Bioquímica), Facultad de Medicina, Universidad de Oviedo, Spain.

Abstract

The causative viral agent of a lethal rabbit hemorrhagic disease has been purified and characterized. In negative-stained preparations, the virions were icosahedral, measured 27 to 35 nm in diameter, were without an envelope, and showed 10 peripheral cup-shaped depressions. The major structural protein was 60 kilodaltons, which constitutes a unique characteristic of the Caliciviridae.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference18 articles.

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3. Physico-chemical evidence for the classification of the caliciviruses;Burroughs J. N.;J. Gen. Virol.,1974

4. Le inside della malattia X del coniglio;Canceflottl F. M.;Riv. Coniglicoltura,1988

5. A gas-liquid-solid phase peptide and protein sequenator;Hewck R. M.;J. Biol. Chem.,1981

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