Seroprevalence of Neutralizing Antibodies to Adenovirus Type 5 among Children in India: Implications for Recombinant Adenovirus-Based Vaccines-Reference-Cited by-同舟云学术

Seroprevalence of Neutralizing Antibodies to Adenovirus Type 5 among Children in India: Implications for Recombinant Adenovirus-Based Vaccines

Published:2007-08 Issue:8 Volume:14 Page:1053-1055
ISSN:1556-6811
Container-title:Clinical and Vaccine Immunology
language:en
Short-container-title:Clin Vaccine Immunol

Author:

Appaiahgari Mohan Babu¹²,Pandey Ravindra Mohan¹²,Vrati Sudhanshu¹²

Affiliation:

1. National Institute of Immunology, New Delhi 110 067, India

2. Department of Biostatistics, All India Institute of Medical Sciences, New Delhi 110 016, India

Abstract

ABSTRACT We determined the levels of adenovirus 5 (Ad5) neutralizing antibodies in children in India less than 2 years of age. The results clearly show an age-dependent increase in Ad5-specific immunity, with 7- to 12-month-old children having the lowest levels of Ad5 immunity. This opens up the scope for the use of recombinant Ad5-based vaccines in this age group.

Publisher

American Society for Microbiology

Subject

Microbiology (medical),Clinical Biochemistry,Immunology,Immunology and Allergy

Link

https://journals.asm.org/doi/pdf/10.1128/CVI.00173-07

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