Hepatitis C Virus-Like Particle Morphogenesis-Reference-Cited by-同舟云学术

Hepatitis C Virus-Like Particle Morphogenesis

Published:2002-04-15 Issue:8 Volume:76 Page:4073-4079
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Blanchard Emmanuelle¹,Brand Denys¹,Trassard Sylvie²,Goudeau Alain¹,Roingeard Philippe¹²

Affiliation:

1. Laboratoire de Virologie et

2. Laboratoire de Biologie Cellulaire, E3M-EA3250, IFR 82, Faculté de Médecine et Centre Hospitalier Universitaire, Tours, France

Abstract

ABSTRACT Although much is known about the hepatitis C virus (HCV) genome, first cloned in 1989, little is known about HCV structure and assembly due to the lack of an efficient in vitro culture system for HCV. Using a recombinant Semliki forest virus replicon expressing genes encoding HCV structural proteins, we observed for the first time the assembly of these proteins into HCV-like particles in mammalian cells. This system opens up new possibilities for the investigation of viral morphogenesis and virus-host cell interactions.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.76.8.4073-4079.2002

Reference27 articles.

1. Bartenschlager, R., and V. Lohman. 2000. Replication of hepatitis C virus. J. Gen. Virol. 81 : 1631-1648.

2. Bartenschlager, R., and V. Lohman. 2001. Novel cell culture systems for the hepatitis C virus. Antivir. Res. 52 : 1-17.

3. Hepatitis C Virus Structural Proteins Assemble into Viruslike Particles in Insect Cells

4. Blight, K.-J., A. A. Kolykhalov, and C. M. Rice. 2000. Efficient initiation of HCV RNA replication in cell culture. Science 290 : 1972-1974.

5. Brand, D., F. Lemiale, G. Thibault, B. Verrier, S. Lebigot, P. Roingeard, L. Buzelay, and F. Barin. 2000. Antigenic properties of recombinant envelope glycoproteins derived from T-cell-line adapted isolates or primary human immunodeficiency virus isolates and their relationship to immunogenicity. Virology 271 : 350-362.

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