Coinfection of Chickens with H9N2 and H7N9 Avian Influenza Viruses Leads to Emergence of Reassortant H9N9 Virus with Increased Fitness for Poultry and a Zoonotic Potential-Reference-Cited by-全球学者库

Coinfection of Chickens with H9N2 and H7N9 Avian Influenza Viruses Leads to Emergence of Reassortant H9N9 Virus with Increased Fitness for Poultry and a Zoonotic Potential

Published:2022-03-09 Issue:5 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Bhat Sushant¹,James Joe²^ORCID,Sadeyen Jean-Remy¹,Mahmood Sahar²,Everest Holly J.²,Chang Pengxiang¹,Walsh Sarah K.²,Byrne Alexander M. P.²,Mollett Benjamin²,Lean Fabian²,Sealy Joshua E.¹,Shelton Holly¹^ORCID,Slomka Marek J.²,Brookes Sharon M.²,Iqbal Munir¹^ORCID

Affiliation:

1. Avian Influenza Group, The Pirbright Institute, Woking, United Kingdom

2. Virology Department, Animal & Plant Health Agency, Weybridge, United Kingdom

Abstract

We evaluated the consequences of reassortment between the H7N9 and the contemporary H9N2 viruses of the G1 lineage that are enzootic in poultry across the Indian subcontinent and the Middle East. Coinfection of chickens with these viruses resulted in the emergence of novel reassortant H9N9 viruses with genes derived from both H9N2 and H7N9 viruses.

Funder

Department for Environment, Food and Rural Affairs, UK Government

UKRI | Biotechnology and Biological Sciences Research Council

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01856-21

Reference112 articles.

1. Epidemiology of Human Infections with Avian Influenza A(H7N9) Virus in China

2. Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus