Purification and Characterization of Alkaline Xylanases from Bacillus polymyxa

Author:

Morales P.1,Madarro A.1,Pérez-González J. A.1,Sendra J. M.1,Piñaga F.1,Flors A.1

Affiliation:

1. Instituto de Agroquímica y Tecnología de Alimentos, Consejo Superior de Investigaciones Científicas, Jaime Roig 11, 46010 Valencia, Spain

Abstract

By applying different classical and fast protein liquid chromatographic techniques, three xylanases (β-1,4- d -xylan xylanhydrolase) were purified to homogeneity from the extracellular enzymatic complex of Bacillus polymyxa . The three enzymes (X 34 C, X 34 E, and X 22 ) were small proteins of 34, 34, and 22 kDa and basic pIs 9.3, >9.3, and 9.0, respectively. X 34 C and X 34 E are closely related and seem to be isoforms of the same enzyme. However, they differ in some characteristics. The three enzymes had different pH and temperature optima. One of them, X 34 E, showed a high thermal stability. The V max values determined for X 34 C, X 34 E, and X 22 enzymes on oat spelts xylan were 14.9, 85.5, and 64.0 U mg -1 , respectively, and 16.1, 62.0, and 150.6 U mg -1 on birchwood xylan. When oat spelts xylan was the substrate used, K m values of 3.4, 2.4, and 1.9 mg ml -1 were obtained for X 34 C, X 34 E, and X 22 enzymes, respectively, and 0.65, 6.3, and 0.32 mg ml -1 were the respective K m values determined with birchwood xylan as the substrate. The enzymes were nondebranching endo-β-xylanases. Xylose was one of the products of xylan hydrolysis by xylanases X 34 C and X 34 E, but this monosaccharide was not released by X 22 enzyme. However, neither of the enzymes was able to degrade xylobiose.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

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