Affiliation:
1. N.N. Petrov National Medical Research Center of Oncology; Saint-Petersburg State University
2. N.N. Petrov National Medical Research Center of Oncology
3. N.N. Petrov National Medical Research Center of Oncology; Saint-Petersburg State Pediatric Medical University
4. Saint-Petersburg State University
Abstract
Aim: This study aimed to clarify the ultrasound semiotics of colorectal cancer liver metastases contrast enhancement, and perform a comparative assessment of the diagnostic efficacy of contrast-enhanced ultrasound and computed tomography (CT).Methods: We studied 40 patients with colorectal cancer: patients receiving treatment for the disease and having newly diagnosed colorectal cancer. All patients underwent contrast-enhanced ultrasound and CT. In the cases of suspected malignancy, a trephine biopsy and a morphological examination were performed.Results: Contrast-enhanced ultrasound and CT demonstrated comparable and high diagnostic efficacy. The sensitivity of the contrast-enhanced ultrasound in malignancy detection was 93.3%, with 90% specificity, 96.55% positive predictive value, 81.82% negative predictive value, and 92.5% accuracy. The sensitivity of contrast-enhanced CT was 93.3%, with 80% specificity, 93.33% positive predictive value, 80% negative predictive value, and 92.5% accuracy.Conclusions: For patients with colorectal cancer with contraindications to contrast-enhanced CT, contrast-enhanced ultrasound may be used an alternative imaging option for the differential diagnosis of liver neoplasms.
Publisher
Annals of Surgical Hepatology
Subject
Gastroenterology,Hepatology,Surgery
Reference20 articles.
1. Sung H., Ferlay J., Siegel R.L., Laversanne M., Soerjomataram I., Jemal A., Bray F. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 2021; 71 (3): 209–249. https://doi.org/10.3322/caac.21660
2. Kovaleva E.V., Sinyukova G.T., Danzanova T.Yu., Lepedatu P.I., Gudilina E.A. The possibilities of contrast-enhaced ultrasound (CEUS) in the diagnosis of colorectal liver metastases (CRLM). Koloproktologia. 2018; 1: 36–41. https://doi.org/10.33878/2073- 7556-2018-0-1-36-41 (In Russian)
3. Gorchakov S.V., Pravosudov I.V., Vasiljev S.V., Oleynik V.V., Popov D.E., Golubev K.V., Zhukov O.A. Modern approach to treatment of colorectal cancer patients with liver metastases (literature review). Vestnik of Saint Petersburg University. Medicine. 2015; 3: 55–68. (In Russian)
4. Engstrand J., Nilsson H., Strömberg C., Jonas E., Freedman J. Colorectal cancer liver metastases – a population-based study on incidence, management and survival. BMC Cancer. 2018; 18 (1): 78. https://doi.org/10.1186/s12885-017-3925-x
5. Engstrand J., Strömberg C., Nilsson H., Freedman J., Jonas E. Synchronous and metachronous liver metastases in patients with colorectal cancer – towards a clinically relevant definition. World J. Surg. Oncol. 2019; 17 (1): 228. https://doi.org/10.1186/s12957-019-1771-9
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献