Malignant pleural mesothelioma: an update

Author:

N. M. Hajj1,2 Glaucia1,H. Cavarson1,2 Carolina1,Lopes Pinto3 Clóvis Antônio2,Venturi1,4 Gabriela3,Navarro4 João R.4,C. Cordeiro de Lima2,5 Vladmir5

Affiliation:

1. 1. Instituto International de Pesquisa, A.C. Camargo Cancer Center, São Paulo (SP), Brasil. 2. Instituto Nacional de Oncogenômica e Inovação, São Paulo (SP), Brasil.

2. 3. Departamento de Patologia Anatômica, A.C. Camargo Cancer Center, São Paulo (SP), Brasil.

3. 1. Instituto International de Pesquisa, A.C. Camargo Cancer Center, São Paulo (SP), Brasil. 4. BP Mirante, São Paulo (SP), Brasil.

4. 4. BP Mirante, São Paulo (SP), Brasil.

5. 2. Instituto Nacional de Oncogenômica e Inovação, São Paulo (SP), Brasil. 5. Rede D’Or, São Paulo (SP), Brasil.

Abstract

Malignant mesotheliomas are rare types of cancers that affect the mesothelial surfaces, usually the pleura and peritoneum. They are associated with asbestos exposure, but due to a latency period of more than 30 years and difficult diagnosis, most cases are not detected until they reach advanced stages. Treatment options for this tumor type are very limited and survival ranges from 12 to 36 months. This review discusses the molecular physiopathology, current diagnosis, and latest therapeutic options for this disease.

Publisher

Sociedade Brasileira de Pneumologia e Tisiologia

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