A comprehensive review on advancements in tissue engineering and microfluidics toward kidney-on-chip

Author:

Sateesh Jasti12ORCID,Guha Koushik1,Dutta Arindam3,Sengupta Pratim4,Yalamanchili Dhanya5,Donepudi Nanda Sai5,Surya Manoj M.1,Sohail Sk. Shahrukh1

Affiliation:

1. Department of Electronics and Communication Engineering, National MEMS Design Centre, National Institute of Technology Silchar, Assam 788010, India

2. Department of Electronics and Communication Engineering, Velagapudi Ramakrishna Siddhartha Engineering College, Kanuru, Vijayawada, India

3. Urologist, RG Stone Urology and Laparoscopic Hospital, Kolkata, West Bengal, India

4. Nephrologist, Belle Vue Clinic, Kolkata, West Bengal, India

5. Medical Interns, Government Siddhartha Medical College, Vijayawada, India

Abstract

This review provides a detailed literature survey on microfluidics and its road map toward kidney-on-chip technology. The whole review has been tailored with a clear description of crucial milestones in regenerative medicine, such as bioengineering, tissue engineering, microfluidics, microfluidic applications in biomedical engineering, capabilities of microfluidics in biomimetics, organ-on-chip, kidney-on-chip for disease modeling, drug toxicity, and implantable devices. This paper also presents future scope for research in the bio-microfluidics domain and biomimetics domain.

Publisher

AIP Publishing

Subject

Condensed Matter Physics,General Materials Science,Fluid Flow and Transfer Processes,Colloid and Surface Chemistry,Biomedical Engineering

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