Combined endoscopic treatment of a patient with cancer of the hypopharynx to the upper third of the esophagus with complete clinical and endoscopic effect

Abstract

We present a clinical case with a complete endoscopic and clinical effect after endoscopic treatment of a patient with laryngeal cancer involving the upper third of the esophagus. The patient was treated as follows: conformal radiation therapy TFD = 40 gr, targeted chemotherapy using Cetuximab (total dose of 1800 mg). 1.5 months after the end of the treatment, a residual laryngopharyngeal tumor with a spread into the upper third of the esophagus was found during videolaryngoscopy examination. The result of the following histological examination was G2 squamous cell carcinoma. From August 2015 to February 2017, the patient underwent 8 photodynamic therapy sessions in combination with argon plasma coagulation. A control videolaryngoscopy, carried out 1 month after the fnal session, showed complete tumor regression without cicatricial deformity and narrowing of the esophageal lumen.