Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis

Author:

Loayza-Castro Joan A1ORCID,Vásquez-Romero Luisa Erika Milagros1ORCID,Zeñas-Trujillo Gianella Zulema1ORCID,Vera-Ponce Victor Juan1ORCID,Torres-Malca Jenny Raquel1ORCID,Guillén-Ponce Norka Rocío1ORCID,Guerra Valencia Jamee1ORCID,Ramos Willy1ORCID,De La Cruz-Vargas Jhony A1ORCID

Affiliation:

1. Instituto de Investigaciones en Ciencias Biomédicas, Universidad Ricardo Palma, Lima, PERU

Abstract

<b>Introduction: </b>Obstructive sleep apnea (OSA) is related to chronic kidney disease (CKD), but its association is not fully understood.<br /> <b>Objective</b>: To realize a systematic review with meta-analysis to determine the association between OSA and CKD.<br /> <b>Methods:</b> Systematic review with meta-analysis of observational studies. The search was carried out in Embase, PubMed/Medline, Scopus, and Web of Science. The data were calculated by the hazard ratio (HR). The heterogeneity was identified by I squared.<br /> <b>Results:</b> Five studies were included (n=6,710). The meta-analysis found an association between OSA and CKD (HR=2.00; confidence interval 95%=1.68-2.38).<br /> <b>Conclusions:</b> We found an association between OSA and CKD.

Publisher

Modestum Ltd

Subject

General Medicine

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