Cention N Compared to Other Contemporary Tooth-Colored Restorative Materials in Terms of Fluoride Ion Releasing Efficacy: Validation of a Novel Caries-Prevention-Initiative by the Ministry of Health, Malaysia

Abstract

Background: The Dental Public Health Services of the Ministry of Health, Malaysia have introduced Cention N as a primary restorative material in the health care centers all over the country. Thus, in this scenario, a comprehensive evaluation of Cention N as compared to other restorative materials, in terms of fluoride release, assumes to be of utmost relevance. Fluoride release plays a pivotal role in the prevention of secondary dental caries, and dental restorations facilitate direct fluoride delivery to the susceptible tooth surface. Aim: To evaluate and compare the fluoride releasing property of Cention N with other restorative materials, EQUIA Forte, Beautifil II and Estelite Quick. Methods and Material: A total of 20 disk-shaped brass-mold samples (6±0.1mm in diameter and 2±0.1mm thickness) for the dental restorative materials were prepared, with five samples for each of Cention N, EQUIA Forte, Beautifil II and Estelite Quick. Following the immersion of samples in deionizing water, the released fluoride ions were measured over 28 days using ion chromatography. Data were obtained at day 1, 7 and 28 post-immersion. Statistical analysis: Data obtained from this investigation was analyzed using the MedCalc statistical software (v. 19.05). Kolmogorov-Smirnove test followed by Repeated Measures ANOVA and ‘Comparison of multiple method’ was applied to statistically compare the fluoride release efficacy of Cention N individually with each of the other three materials. Any difference found was considered significant at P<0.05. Results: Cention N showed significantly higher fluoride release than Beautifil II and Estelite Quick when observed on Day 1, 7 and 28. ‘Comparison of multiple method’ confirmed the results obtained via ANOVA and showed Cention N is a significantly better (P<0.05) material in terms of fluoride release as compared to Beautifil II and Estelite Quick on Day 1, 7 and 28. Conclusions: Cention N displays consistent fluoride release while weighing against other contemporary and more expensive restorative materials.