Microwave-irradiated synthesis and Biological applications of Transition metal (II) complexes of Unsymmetrical Quadridentate (ON NO donor) Schiff base ligand

Abstract

An efficient and environmentally benign method using microwave irradiation (MWI) have been applied for the synthesis of mononuclear square planar transition metal (II) [e.g. Co2+, Ni2+ and Cu2+] complexes with an unsymmetrical tetradentate bi-anionic Schiff base ligand. All the eco-friendly synthesized transition metal complexes were characterised by elemental analysis, conductivity & magnetic moment measurements and common spectroscopic methods (vis. IR, UV-Visible and 1H NMR spectroscopy respectively). The biological evaluation as anti-bacterial and human pathogenic anti-fungal activities of the investigating compounds show that the investigated complexes were found to be far active than the ligand towards tested microbes under the identical experimental conditions and the antimicrobial activity trend follows the order: Cu-complex > Co-complex > Ni-complex > Ligand