Affiliation:
1. Department of Chemistry, University of Rajasthan, Jaipur, Rajasthan India.
Abstract
Randia Genus (Indigo berry) belongs to family Rubiaceae, native to America, allocated in tropical regions. Most of the Species associated with this Genus used as ornamental, folk medicine to treat the disease of renal, malaria, cancer, dysentery, snake-bite etc. All plant parts are used by tribes for various ailment treatments. The phytochemicals generally associated with this genus are terpenoids, saponins, lignans, coumarin, iso-coumarin, flavonoids, tannins, essential oil and acid resin. This review highlights the phytochemicals and pharmacological activity reports. Phytochemical investigation of Randia dumetorum fruit extract using petroleum ether solvent, reveals the presence of 2,4-di-tert-butylphenol, octadecadienoic acid, 23(Phenylsulfanyl) lanosta-8,24-dien-3-ol, hexadecenoic acid, gamma-sitosterol, 4-tert-butylcalix[4]arene, tetracontane, tetratetracontane and octacosanol etc. Compound 1-Octacosanol (A), 9-Octadecenoic acid (B) and gamma-Sitosterol (C) were isolated with the help of column chromatographic techniques and characterized by spectral studies i.e. 1H NMR, 13C NMR, IR and mass spectroscopy.
Publisher
Oriental Scientific Publishing Company
Subject
Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry
Reference17 articles.
1. 1. Marina, D.J.; Ana, M.G.; and Roberto, S., A New Species of Randia (Rubiaceae) and the Taxonomic Significance of Foliar Anatomy in the Species of Randia of the Southern Cone of America. Systematic Botany 2020, 45 (3), 607–619.
2. 2. Daiane, M.; and Cecilia, V.N., Secondary Metabolites from Rubiaceae Species. Molecules 2015, 20, 13422-13495.
3. 3. Jaswant, S.S.; and Sood, S.K., Ethnomedicinal Plants Used to Treat Skin Ailments in Fringe Villages of Col. Sher Jung National Park, Simbalbara, Sirmour, Himachal Pradesh, India. Journal of Bioresearch 2023, 2(1), 1-10.
4. 4. Ayala, M.O.; Camacho, S.G.; and Vargus, F.D., Phytochemical composition and biological activities of the plants of the genus Randia. Botanical Sciences 2022, 100 (4), 779-796.
5. 5. Timalsina, D.; Devkota, H.P.; Bhusal, D.; and Sharma, K.R., Catunaregam spinosa (Thunb.) Tirveng: A Review of Traditional Uses, Phytochemistry, Pharmacological Activities, and Toxicological Aspects. Evidence-Based Complementary and Alternative Medicine 2021, 3257732.