Recent advancements in skin cancer treatment: a critical review

Author:

Goyal Rajat1ORCID,Husain Shaheen2ORCID,Wilson Kashish1ORCID,Chopra Hitesh3ORCID,Pahwa Rakesh4ORCID,Loganathan Mathumalar5ORCID,Sharma Rohit6ORCID

Affiliation:

1. MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala 133207, Haryana, India

2. Amity Institute of Nanotechnology, Amity University Uttar Pradesh (AUUP), Noida 201313, Uttar Pradesh, India

3. Department of Biosciences, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai 602105, Tamil Nadu, India

4. Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra 136119, Haryana, India

5. Faculty of Pharmacy, Puncak Alam Campus, Universiti Teknologi MARA (UiTM), Shah Alam 40450, Malaysia

6. Department of Rasashastra and Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India

Abstract

The prevalence of skin cancer has increased hastily in the recent decade for both kinds of melanoma and non-melanoma skin cancer. Skin cancers mostly encompass keratinocyte cancers: cutaneous squamous cell carcinoma, basal cell carcinoma, and melanoma. This review discusses the recent advancements in the treatment of skin cancer. In addition to chemotherapy, immunotherapy, targeted therapy, and photodynamic therapy (PDT), there are several other therapies for skin cancer. Additionally, PDT use in combination with chemotherapy, radiation, immunotherapy, and surgery is being actively investigated. This review will specifically address the pathophysiology of skin cancer, diagnostic approaches, and current therapies used in the topical treatment of skin cancers and introduce emerging treatment using nanotechnology that may be beneficial for these indications.

Publisher

Open Exploration Publishing

Subject

Molecular Medicine

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