Characterization of an antithrombotic peptide from α-casein in newborn plasma after milk ingestion

Author:

Chabance Beathice,Jollès Pierre,Izquierdo Carmen,Mazoyer Elisabeth,Francoual Christine,Drouet Ludovic,Fiat Anne-Marie

Abstract

Bovine and human k-caseinoglycopeptides, two antithrombotic peptides derived from the corresponding k-caseins, were detected in physiologically active concentrations in the plasma of 5-d-old newborn infants after ingestion of cow's-milk-based formula or human milk respectively. It is suggested that these two bioactive peptides are released from milk proteins during digestion.

Publisher

Cambridge University Press (CUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference14 articles.

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3. Biologically Active Peptides from Milk Proteins with Emphasis on Two Examples Concerning Antithrombotic and Immunomodulating Activities

4. Further Evidence for the Formationin vivoof Phosphopeptide in the Intestinal Lumen from Dietaryβ-Casein

5. Stan E. Y. & Chernikov M. P. (1982). Formation of a peptide inhibitor of gastric secretion from rat milk proteins in vivo. Bulletin of Experimental Biological Medicine (Translated from Byulleten' Eksperimental' noi Biologii i Meditsiny) 94, 1087–1089.

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