A next-generation mt-sDNA test had 94% sensitivity for colorectal cancer and 91% specificity for advanced neoplasia
Author:
Affiliation:
1. University of Alberta, Edmonton, Alberta, Canada (S.V.V.)
2. Nanyang Technological University, Lee Kong Chian School of Medicine, Singapore (E.J.K.)
Publisher
American College of Physicians
Link
https://www.acpjournals.org/doi/pdf/10.7326/ANNALS-24-01660-JC
Reference3 articles.
1. Hol L, van Leerdam ME, van Ballegooijen M, et al. Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy. Gut. 2010;59:62-68. [PMID: 19671542]
2. Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370:1287-1297. [PMID: 24645800]
3. de Klaver W, Wisse PH, van Wifferen F, et al. Clinical validation of a multitarget fecal immunochemical test for colorectal cancer screening: a diagnostic test accuracy study. Ann Intern Med. 2021;174:1224-1231. [PMID: 34280333]
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