The Effects of Rosemary (Rosmarinus officinalis L.) Extract on the Oxidant Stress Indexes and Proliferation Capacities of SW1353 Chondrosarcoma Cells

Author:

CECEN Berivan1ORCID,KOZACI Leyla Didem2ORCID

Affiliation:

1. Rowan University

2. ANKARA YILDIRIM BEYAZIT ÜNİVERSİTESİ

Abstract

Arthritis is characterized by symptoms such as joint pain, swelling, and limitation of movement. The main objectives of treating the disease are eliminating pain and inflammation and protecting joint functions. Several herbal remedies have been reported to be applied in specific forms to treat arthritis or prevent some ailments. In this study, the effects of rosemary extract (RE) were examined in terms of proliferation capacity, total antioxidant status (TAS) and total oxidant status (TOS) and oxidative stress index (OSI) on SW1353 cell line to see whether rosemary extract can be used in the treatment of arthritis. The cytotoxic effect of RE, which appears in high doses, draws attention to its pharmacovigilance in its use. Our findings indicate that RE at low concentrations, regardless of its antioxidant proper- ties, may be utilized to treat arthritis associated with cartilage damage.

Publisher

Erciyes Universitesi

Subject

General Earth and Planetary Sciences,General Engineering,General Environmental Science

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