New possibilities of perimetry in screening and early diagnosis of glaucoma

Author:

Simakova I. L.1ORCID,Kulikov A. N.1ORCID,Serdiukova S. A.2ORCID,Gorbacheva K. S.3ORCID,Grigoryan L. A.4ORCID

Affiliation:

1. S.M. Kirov Military Medical Academy, Academic Department of Ophthalmology

2. S.M. Kirov Military Medical Academy, Ophthalmological Department of the Clinical and Diagnostic Polyclinic of the Medical and Diagnostic Center

3. OOO Inkerman

4. OOO Total Vizhen

Abstract

PURPOSE. To study the diagnostic effectiveness of an improved software version of the well-known authors' modification of Frequency Doubling Technology (FDT) perimetry by comparing it with the previous software version and standard automated perimetry on the same contingent of healthy individuals and patients with primary open-angle glaucoma (POAG).METHODS. The study included 56 patients (105 eyes) (mean age 61±13.2 years) with POAG. Patients were divided into three groups depending on the stage of glaucoma: group 1 — early stage (39 eyes), group 2 — moderate (25 eyes), and group 3 — advanced (9 eyes) stage. The fourth (control) group included 32 eyes of 16 healthy people (average age 48.2±6.2 years). All study subjects underwent standard automated perimetry (SAP) on the Humphrey III visual field analyzer and non-standard perimetry in the form of our own modification of FDT perimetry and its improved software version — FDT VR version based on the new portable automatic perimeter "Stimulus" (OOO Total Vizhen, Russia). The optic nerve disc was evaluated on the Heidelberg Retina Tomograph 3.RESULTS. The software version of the authors' modification of FDT perimetry has been improved for liquid crystal monitors and adapted to the portable perimeter "Stimulus". When comparing diagnostic effectiveness, both variants of FDT perimetry are not inferior to SAP in sensitivity (87.6; 87.8 and 86.7%, respectively), and in terms of specificity (98.2; 98.1 and 84.4%, respectively) they are superior. A strong (r=0.99988) and reliable (p<0.05) correlation was found between the average values of light sensitivity for both variants of FDT perimetry.CONCLUSION. The introduction of FDT perimetry based on the new portable automatic perimeter "Stimulus" into widespread ophthalmological practice can contribute to improving the effectiveness of screening and early diagnosis of glaucoma.

Publisher

Research Institute of Eye Diseases

Reference27 articles.

1. Weinreb R., Greve E., eds. Glaucoma diagnosis: structure and function: the 1th consensus report of the world glaucoma association. Amsterdam, the Netherlands: Kugler Publications; 2004; 162 p.

2. Volkov V.V. On the standards for an assessment of existence, course and treatment of glaucoma according to recommendations of experts of the International association of glaucoma societies (part І). National Journal glaucoma 2012; 2:60-64.

3. Volkov V.V. On the standards for an assessment of existence, course and glaucoma treatment according to recommendations of experts of the International association of glaucoma societies (part 2). National Journal glaucom 2012; 3:48-52.

4. Volkov V.V. Glaukoma otkrytougol´naya [Open-angle glaucoma]. Moscow, Medicinskoe informacionnoe agentstvo, 2008. 347 p.

5. Simakova I.L., Sukhinin M.V., Serdukova S.A. The effectiveness of various methods of computerized perimetry in primary open-angle glaucoma. Part 1. National Journal glaucoma 2016; 15(1):25-36.

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