Intraocular Pressure Lowering Associated With Worsening Optic Pit-Like Retinoschisis

Abstract

In this article, we present a case of optic pit-like macular retinoschisis in the absence of advanced glaucomatous cupping. Intraocular pressure (IOP)-lowering therapy, which was started due to an early concern for glaucoma, caused a worsening of the retinoschisis, which subsequently resolved on discontinuation of the IOP-lowering therapy. Lower IOP likely triggered intraretinal fluid accumulation by facilitating a translaminar gradient from the subarachnoid to intraretinal space. [ Ophthalmic Surg Lasers Imaging Retina 2024;55:XX–XX.]