Ovarian reserve in obese patients: where do the eggs disappear?

Abstract

Currently, the issue of obesity and its impact on various aspects of human health is actively being discussed. The role of obesity in the development of metabolic syndrome is well known. Within the study of the obesity pandemic, the modern medical community is conducting research in the field of reproductive health. In women, markers of ovarian reserve are considered, with the main one being the level of anti-Mullerian hormone (AMH). It is known that with age, the number of AMH and antral follicles in a woman's body decreases. However, there is data in the modern literature indicating a decrease in ovarian reserve parameters in conditions of weight gain. Weight gain is accompanied by a imbalance of adipokines - biologically active substances produced mainly by adipose tissue and other tissues of the body that affect metabolic processes. It can be assumed that a deep study of the relationship between decreased reproductive potential and obesity, timely prevention of metabolic disorders will improve fertility indicators.