1. Role of prostaglandins in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine;Sharon, P.; Ligumsky, M.; Rachmilewitz, D.;Gastroenterology,1978
2. Enhanced thromboxane A2 and prostacyclin production by cultured rectal mucosa in ulcerative colitis and its In the cell suspensions obtained from the inhibition by steroids and sulfasalazine. Gastrochronically inflamed mucosa of inflammatory bowel disease patients and from normal subjects, polymorphonuclear cells were not identified. This is in agreement with the established observation that mononuclear cells predominate in chronic inflammatory conditions. The addition of lipopolysaccharide to the medium also did not stimulate prostanoid synthesis by enterology;Ligumsky, M.; Karmeli, F.; Sharon, P.,1981
3. Enhanced intestinal prostanoid synthesis in Crohn's disease;Rachmilewitz, D.; Karmeli, F.; Zifroni, A.;(Abstract). Gastroenterology,1982
4. The role of arachidonic acid metabolites in inflammation;Higgs, G.A.; Moncada, S.; Vane, JR,1979
5. The immunologv of inflanintestinal mononucler cells. This observation further matory bowel disease. Progress in gastroenterology supports the contention that mononuclear cells responsible for most of the intestinal prostanoid production are different from adherent phagocytic cells. In conclusion, the cumulative data suggest that mononuclear cells have an important role in prostanoid synthesis by normal colonic mucosa as well as by the inflamed intestinal mucosa in inflammatory;Strickland, R.G.; Sachar, D.B.,1977