Significant associations of antidrug antibody levels with serum drug trough levels and therapeutic response of adalimumab and etanercept treatment in rheumatoid arthritis

Author:

Chen Der-Yuan,Chen Yi-Ming,Tsai Wen-Chan,Tseng Jui-Cheng,Chen Yi-Hsing,Hsieh Chia-Wei,Hung Wei-Ting,Lan Joung-Liang

Publisher

BMJ

Subject

General Biochemistry, Genetics and Molecular Biology,Immunology,Immunology and Allergy,Rheumatology

Reference52 articles.

1. Joint inflammation and cytokine inhibition in rheumatoid arthritis;Christodoulou;Clin Exp Med,2006

2. Cytokine pathways and joint inflammation in rheumatoid arthritis;Choy;N Engl J Med,2001

3. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases;Feldmann;Nat Med,2003

4. TEMPO Study Investigators: Comparison of etanercept and methotrexate, alone and combined, in the treatment of rheumatoid arthritis: Two-year clinical and radiographic results from the TEMPO study, a double-blind, randomized trial;van der Heijde,2006

5. The PREMIER study: a multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment;Breedveld;Arthritis Rheum,2006

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