AB0889 SARCOPENIA AND HIP FRACTURE IN GERIATRIC POPULATION

Abstract

Background:Sarcopenia is a loss of skeletal muscle mass, muscle strength, and function, with an impact on the quality of life, increased risk of bone loss and fracture, which is associated with normal aging.Objectives:To determine the effect of sarcopenia on the recovery of patients after hip fracture, their fitness, functionality, and quality of lifeMethods:A prospective study had 60 patients with hip fractures of both sexes,> 65 years of age (70.8), in the experimental group of patients with sarcopenia and the control group without sarcopenia. All anthropometric measurements were performed: BMI (kg / m2), waist circumference, the volume of the upper arm and lower leg muscle mass, handgrip force (kg) - dynamometry. The following questionnaires were used to assess functionality, mobility, and quality of life: Health assessment questionnaire (HAQ), Harrison hip score (HHS), Sarcopenia and Quality of life (SarQol)Results:Muscle mass (BMI) was significantly lower in the experimental group patients (p <0.005) compared to the control group. The clamp strength measured by the dynamometer was significantly lower in patients with hip fractures (p <0.005) compared to the control group. About 2/3 of the subjects with sarcopenia and hip fracture have a severe and complete physical disability. There was a significant difference in all domains of quality of life between subjects with hip fractures and the control group due to the presence of sarcopenia (p <0.005).Conclusion:The presence of sarcopenia indicates consequently reduced functionality and a degree of disability in patients with hip fractures, slows recovery and increases the need for mobility aids, thus extending hospital stay and patient recovery.References:[1]He H, Liu Y, Tian Q, Papasian CJ, Hu T, Deng HW. Relationship of sarcopenia and body composition with osteoporosis. Osteoporos Int. 2016 Feb; 27(2):473–82.https://doi.org/10.1007/s00198-015-3241-8PMID: 26243357[2]Oliveira A, Vaz C. The role of sarcopenia in the risk of osteoporotic hip fracture. Clin Rheumatol. 2015 Oct; 34(10):1673–80.https://doi.org/10.1007/s10067-015-2943-9PMID: 25912213[3]Tarantino U, Piccirilli E, Fantini M, Baldi J, Gasbarra E, Bei R. Sarcopenia and fragility fractures: molecular and clinical evidence of the bone-muscle interaction. J Bone Joint Surg Am. 2015 Mar 4; 97(5):429–37.https://doi.org/10.2106/JBJS.N.00648PMID: 25740034 Benichou O, Lord SR. Rationale for Strengthening Muscle to Prevent Falls and Fractures: A Review of the Evidence. Calcif Tissue Int. 2016 Jun; 98(6):531–45.https://doi.org/10.1007/s00223-016-0107-9PMID: 26847435[4]Hirschfeld HP, Kinsella R, Duque G. Osteosarcopenia: where bone, muscle, and fat collide. Osteoporos Int. 2017 Oct; 28(10):2781–2790.https://doi.org/10.1007/s00198-017-4151-8PMID: 28733716[5]Rantanen T, Volpato S, Ferrucci L, Heikkinen E, Fried LP, Guralnik JM. Handgrip strength and causespecific and total mortality in older disabled women: exploring the mechanism. J Am Geriatr Soc. 2003 May; 51(5):636–41.https://doi.org/10.1034/j.1600-0579.2003.00207.xPMID: 12752838[6]Syddall H, Cooper C, Martin F, Briggs R, Aihie Sayer A. Is grip strength a useful single marker of frailty? Age Ageing. 2003 Nov; 32(6):650–6.https://doi.org/10.1093/ageing/afg111PMID: 14600007[7]Chen LK, Liu LK, Woo J, Assantachai P, Auyeung TW, Bahyah KS, et al. Sarcopenia in Asia: consensus report of the Asian Working Group for Sarcopenia. J Am Med Dir Assoc. 2014 Feb; 15(2):95–101.https://doi.org/10.1016/j.jamda.2013.11.025PMID: 24461239[8]Wehren LE, Hawkes WG, Hebel JR, Orwig DL, Magaziner J. Bone mineral density, soft tissue body composition, strength, and functioning after hip fracture. J Gerontol A Biol Sci Med Sci. 2005 Jan; 60 (1):80–4.https://doi.org/10.1093/gerona/60.1.80PMID: 15741287Disclosure of Interests:None declared