Abstract
The discovery of the protective adaptive response of cells to a low dose of radiation suggests applications to radiation worker/first responder protection. Its use in cancer radiotherapy has been discussed in a separate publication. This paper describes simple changes in scheduling that can make use of these beneficial adaptive effects for protection. No increase in total exposure is necessary, only a simple change in the timing of radiation exposure. A low dose of radiation at a sufficient dose rate will trigger the adaptive response. This in turn will offer a considerable protection against the damage from a subsequent high dose. A simple scenario is discussed as well as a brief review of the experimental basis of the adaptive response.
Reference17 articles.
1. Blankenbecler R, 2011. Computer Prescribed Treatment to Reduce Damage From Radiation Therapy and Chemotherapy. pat. 7963902, issued 6/21/2011.
2. DEVELOPING A SCIENTIFIC BASIS FOR RADIATION RISK ESTIMATES: GOAL OF THE DOE LOW DOSE RESEARCH PROGRAM
3. Cancer Risk from Low-Level Radiation
4. Coleman MA and Wyrobek AJ. 2006. Differential transcript modulation of genes after low vs high doses of ionizing radiation. Adv in Med Phys: Bio Effects of Low Doses of Ionizing Rad. 273–276