Author:
Liu Zhaoyun,Xu Xintong,Liu Hui,Zhao Xianghong,Yang Chun,Fu Rong
Abstract
AbstractMultiple myeloma (MM) is related to immune disorders, recent studys have revealed that immunotherapy can greatly benefit MM patients. Immune checkpoints can negatively modulate the immune system and are closely associated with immune escape. Immune checkpoint-related therapy has attracted much attention and research in MM. However, the efficacy of those therapies need further improvements. There need more thoughts about the immune checkpoint to translate their use in clinical work. In our review, we aggregated the currently known immune checkpoints and their corresponding ligands, further more we propose various ways of potential translation applying treatment based on immune checkpoints for MM patients.
Funder
the National Natural Science Foundation of China Youth Project
the Tianjin Municipal Natural Science Foundation
the Tianjin Education Commission Research Project
the Tianjin Science and Technology Planning Project
the Tianjin Municipal Health Commission Youth Project
Medjaden Academy & Research Foundation for Young Scientists
the Tianjin Key Medical Discipline(Specialty) Construction project
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,Hematology
Cited by
2 articles.
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