Abstract
Abstract
Background
The prevalence of HIV among men who have sex with men (MSM) in southwest China is still increasing. This study aimed to investigate the trend in HIV incidence and its associated risk factors among MSM in Chengdu, China.
Method
Incidence data were collected from the largest local non-governmental organization (NGO) serving MSM in Chengdu between 2012 and 2018, while information on sexual behaviors was collected from 2014. All MSM who received voluntary counseling and testing services (VCT) in the collaborating NGO at least twice during the study period were included. We calculated the HIV incidence density among MSM every 2 years and the overall incidence rate. A Cox proportional hazards regression model was employed to identify risk factors for HIV infection.
Result
A total of 4578 HIV-negative participants were included in the cohort. The total incidence density was 5.95 (95% CI: 5.37–6.56)/100 person-years (PYs) between 2012 and 2018. The segmented incidence density was 9.02 (95% CI: 7.46–10.78), 5.85 (95% CI: 4.86–6.97), 5.43 (95% CI: 4.53–6.46), and 3.09 (95% CI: 2.07–4.41)/100 PYs in 2012–2013, 2014–2015, 2016–2017, and 2018, respectively. After adjusting for sociodemographic characteristics, compared to participants without sexual partners within 6 months, MSM with one fixed partner (Adjusted Hazard Ratio, AHR = 1.18, 95% CI: 0.44–3.19) and more than five partners (AHR = 2.24, 95% CI: 0.81–6.20) had increased risk of HIV infection. MSM who used condom inconsistently had a higher risk of HIV infection (AHR = 1.87, 95% CI: 1.46–2.38) compared to consistent condom users.
Conclusion
The decreased HIV incidence density among MSM was potentially related to the successful comprehensive HIV prevention strategies in Chengdu. Multiple male sexual partnerships and inconsistent condom use during anal intercourse were risk factors associated with HIV occurrence.
Funder
National Natural Science Foundation of China
National Major Science and Technology Projects of China
Science and Technology Planning Project of Guangdong Province
Science and Technology Research Project of Guangzhou
Publisher
Springer Science and Business Media LLC
Subject
Public Health, Environmental and Occupational Health
Reference46 articles.
1. Yang X, Wang Z, Wang X, Ma T, Xue H, He Y, et al. Behavioral intention to initiate antiretroviral therapy (ART) among Chinese HIV-infected men who have sex with men having high CD4 count in the era of "treatment for all". Am J Mens Health. 2019;13(1):1557988319828615. https://doi.org/10.1177/1557988319828615.
2. Alfvén T, Erkkola T, Ghys PD, Padayachy J, Warner-Smith M, Rugg D, et al. Global AIDS Reporting-2001 to 2015: lessons for monitoring the sustainable development goals. AIDS Behav. 2017;21(Suppl 1):5–14. https://doi.org/10.1007/s10461-016-1662-9.
3. Liu Z, Shi O, Yan Q, Fang Q, Zuo J, Chen Y, et al. Changing epidemiological patterns of HIV and AIDS in China in the post-SARS era identified by the nationwide surveillance system. BMC Infect Dis. 2018;18(1):700. https://doi.org/10.1186/s12879-018-3551-5.
4. Zheng S. The growing threat of China's HIV epidemic. Lancet Public Health. 2018;3(7):e311. https://doi.org/10.1016/S2468-2667(18)30098-7.
5. China Health and Family Planning Commission: 2015 China AIDS Response Progress Report In Edited by Commission CHaFP: Center for Disease Control; 2015. Available from: http://www.commuhealtibet.org/wp-content/uploads/2016/11/CHN_narrative_report_2015.pdf
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