Author:
Mansour Razan,Al-Ani Abdallah,Al-Hussaini Maysa,Abdel-Razeq Hikmat,Al-Ibraheem Akram,Mansour Asem H.
Abstract
Abstract
Purpose
This scoping review examines controllable predisposing factors attributable to cancer in the Middle East and North Africa (MENA) region’s adult population, highlighting opportunities to enhance cancer prevention programs.
Design
We systematically searched the PubMed, Science Direct, and CINAHL, EMBASE, and Cochrane Library databases from 1997 to 2022 for articles reporting on the impact of modifiable risk factors on adult patients with cancer in the MENA region.
Results
The review identified 42 relevant articles, revealing that tobacco consumption, obesity, physical inactivity, and diet are significant modifiable risk factors for cancer in the region. Tobacco smoking is a leading cause of lung, bladder, squamous cell carcinoma, and colorectal cancer. A shift towards a westernized, calorie-dense diet has been observed, with some evidence suggesting that a Mediterranean diet may be protective against cancer. Obesity is a known risk factor for cancer, particularly breast malignancy, but further research is needed to determine its impact in the MENA region. Physical inactivity has been linked to colorectal cancer, but more studies are required to establish this relationship conclusively. Alcohol consumption, infections, and exposure to environmental carcinogens are additional risk factors, although the literature on these topics is limited.
Conclusion
The review emphasizes the need for further research and the development of targeted cancer prevention strategies in the MENA region.
Publisher
Springer Science and Business Media LLC
Subject
Public Health, Environmental and Occupational Health
Reference69 articles.
1. World Bank.: World Bank Open Data [Internet]. World Bank Open Data, 2022[cited 2023 Jul 27] Available from: https://data.worldbank.org.
2. World Health Organization.: Cancer - Fact Sheet [Internet], 2022[cited 2023 Aug 1] Available from: https://www.who.int/news-room/fact-sheets/detail/cancer.
3. Sung H, Ferlay J, Siegel RL et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries [Internet]. CA: A Cancer Journal for Clinicians 71:209–249, 2021[cited 2021 Oct 9] Available from: https://onlinelibrary.wiley.com/doi/abs/https://doi.org/10.3322/caac.21660.
4. Naja F, Nasreddine L, Awada S et al. Nutrition in the Prevention of Breast Cancer: A Middle Eastern Perspective [Internet]. Frontiers in Public Health 7, 2019[cited 2023 Jul 27] Available from: https://www.frontiersin.org/articles/https://doi.org/10.3389/fpubh.2019.00316.
5. Mahdi H, Mula-Hussain L, Ramzi ZS et al. Cancer Burden Among Arab-World Females in 2020: Working Toward Improving Outcomes [Internet]. JCO Global Oncology e2100415, 2022[cited 2022 Jun 13] https://doi.org/10.1200/GO.21.00415.