Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort study
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Published:2024-01-25
Issue:1
Volume:24
Page:
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ISSN:1471-2458
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Container-title:BMC Public Health
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language:en
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Short-container-title:BMC Public Health
Author:
Sang Ni,Liu Rong-chao,Zhang Ming-hui,Lu Zong-Xiao,Wu Zhen-Gang,Zhang Meng-Yao,Li Bo-Han,Wei Meng,Pan Hai-Feng,Wu Guo Cui
Abstract
Abstract
Background and aims
The older people bears a severe burden of disease due to frailty and depressive symptoms, however, the results of association between the two in the older Chinese people have been conflicting. Therefore, this study aimed to investigate the developmental trajectories and interactions of frailty and depressive symptoms in the Chinese middle-aged and older adults.
Methods
The study used four waves of data from 2011, 2013, 2015 and 2018 in the China Health and Retirement Longitudinal Study (CHARLS) database, focused on middle-aged and older people ≥ 45 years of age, and analyzed using latent growth models and cross-lagged models.
Results
The parallel latent growth model showed that the initial level of depressive symptoms had a significant positive predictive effect on the initial level of frailty. The rate of change in depressive symptoms significantly positively predicted the rate of change in frailty. The initial level of frailty had a significant positive predictive effect on the initial level of depressive symptoms, but a significant negative predictive effect on the rate of change in depressive symptoms. The rate of change in frailty had a significant positive predictive effect on the rate of change in depressive symptoms. The results of the cross-lagged analysis indicated a bidirectional causal association between frailty and depressive symptoms in the total sample population. Results for the total sample population grouped by age and gender were consistent with the total sample.
Conclusions
This study recommends advancing the age of concern for frailty and depressive symptoms to middle-aged adults. Both men and women need early screening and intervention for frailty and depressive symptoms to promote healthy aging.
Funder
Graduate green seedling cultivation project for School of Nursing, Anhui Medical University
Inflammation and Immune Mediated Diseases Laboratory of Anhui Province
scientific research cultivation project for School of Nursing, Anhui Medical University
Research Fund of Anhui nursing Association
Publisher
Springer Science and Business Media LLC
Subject
Public Health, Environmental and Occupational Health
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