Author:
He Chao-Qun,Sun Bai-Hong,Yu Wang-Tao,An Shu-Yi,Qiao Bao-Jun,Wu Wei
Abstract
Abstract
Background
It is uncertain how COVID-19 outbreak influences the hepatitis B epidemics. This study aims to evaluate the effects on hepatitis B owing to the COVID-19 outbreak and forecast the hepatitis B epidemiological trend in mainland China to speed up the course of the “End viral hepatitis Strategy”.
Methods
We estimated the causal impacts and created a forecast through adopting monthly notifications of hepatitis B each year from 2005 to 2020 in mainland China using the Bayesian structural time series (BSTS) method.
Results
The hepatitis B epidemics fluctuates irregularly during the period 2005–2007(APC = 8.7, P = 0.246) and 2015–2020(APC = 1.7, P = 0.290), and there is a downturn (APC=-3.2, 95% CI -5.2 to -1.2, P = 0.006) from 2007 to 2015 in mainland China. The COVID-19 outbreak was found to have a monthly average reduction on the hepatitis B epidemics of 26% (95% CI 18–35%) within the first three months in 2020,17% (95% CI 7.7–26%) within the first six months in 2020, and 10% (95% CI19–22%) all year as a result of the COVID-19 outbreak, (probability of causal effect = 96.591%, P = 0.034) and the forecasts showed an upward trend from 2021 to 2025 (annual percentage change = 4.18, 95% CI 4.0 to 4.3, P < 0.001).
Conclusion
The COVID-19 has a positive effect on the decline of hepatitis B cases. And the potential of BSTS model to forecast the epidemiological trend of the hepatitis B can be applied in automatic public health policymaking in mainland China.
Funder
the Science Foundation of Liaoning Provincial Department of Education
Publisher
Springer Science and Business Media LLC
Subject
Public Health, Environmental and Occupational Health