Efficacy and safety of rapid intermittent correction compared with slow continuous correction with hypertonic saline in patients with moderately severe or severe symptomatic hyponatremia: study protocol for a randomized controlled trial (SALSA trial)
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Medicine (miscellaneous)
Link
http://link.springer.com/content/pdf/10.1186/s13063-017-1865-z.pdf
Reference33 articles.
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2. Decaux G. Is asymptomatic hyponatremia really asymptomatic? Am J Med. 2006;119(7 Suppl 1):S79–82.
3. Knochel JP. Hypoxia is the cause of brain damage in hyponatremia. JAMA. 1999;281(24):2342–3.
4. Kokko JP. Symptomatic hyponatremia with hypoxia is a medical emergency. Kidney Int. 2006;69(8):1291–3.
5. Fujisawa H, Sugimura Y, Takagi H, Mizoguchi H, Takeuchi H, Izumida H, et al. Chronic hyponatremia causes neurologic and psychologic impairments. J Am Soc Nephrol. 2016;27(3):766–80.
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