Standard: Human intestinal cancer organoids

Author:

Lin Hanqing,Wang Yalong,Cheng Chunyan,Qian Yuxin,Hao Jie,Zhang Zhen,Sheng Weiqi,Song Linhong,Deng Chu-Xia,Zhao Bing,Cao Jiani,Wang Lei,Wang Liu,Liang Lingmin,Chen Wenli Kelly,Yu Chunping,Sun Zhijian,Yang Yingying,Wang Changlin,Zhang Yong,Li Qiyuan,Li Ka,Ma Aijin,Zhao Tongbiao,Chen Ye-Guang,Hua Guoqiang

Abstract

AbstractIntestinal cancer is one of the most frequent and lethal types of cancer. Modeling intestinal cancer using organoids has emerged in the last decade. Human intestinal cancer organoids are physiologically relevant in vitro models, which provides an unprecedented opportunity for fundamental and applied research in colorectal cancer. “Human intestinal cancer organoids” is the first set of guidelines on human intestinal organoids in China, jointly drafted and agreed by the experts from the Chinese Society for Cell Biology and its branch society: the Chinese Society for Stem Cell Research. This standard specifies terms and definitions, technical requirements, test methods for human intestinal cancer organoids, which apply to the production and quality control during the process of manufacturing and testing of human intestinal cancer organoids. It was released by the Chinese Society for Cell Biology on 24 September 2022. We hope that the publication of this standard will guide institutional establishment, acceptance and execution of proper practocal protocols, and accelerate the international standardization of human intestinal cancer organoids for clinical development and therapeutic applications.

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Developmental Biology

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