Management of regional citrate anticoagulation for continuous renal replacement therapy: guideline recommendations from Chinese emergency medical doctor consensus
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Published:2023-05-29
Issue:1
Volume:10
Page:
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ISSN:2054-9369
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Container-title:Military Medical Research
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language:en
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Short-container-title:Military Med Res
Author:
Liu Shu-Yuan, Xu Sheng-Yong, Yin Lu, Yang Ting, Jin Kui, Zhang Qiu-Bin, Sun Feng, Tan Ding-Yu, Xin Tian-Yu, Chen Yu-Guo, Zhao Xiao-Dong, Yu Xue-Zhong, Xu JunORCID, Chen Xu-Feng, Chen Zhi, Dou Qing-Li, Guan Jian, Gui Yao-Song, Huang Zhong-Wei, Li Xiao-Min, Liu Dan-Ping, Lv Jing-Jun, Liu Yong, Qian Chuan-Yun, Shan Yi, Shi Yan, Sun Ming, Wu Hai-Ying, Xia Jian, Xu Feng, Xu Tie, Yan Xian-Liang, Yang Jian-Zhong, Yu Yong-Wu, Zhang Jin-Song, Zhang Mao, Zhang Wei, Zhao Hong-Yu, Zheng Dong-Hui, Zhou Ping, Zhu Bao-Feng, Zhu Hua-Dong, Shen Shi-Qian, Prowle John, Bellgardt Martin,
Abstract
AbstractContinuous renal replacement therapy (CRRT) is widely used for treating critically-ill patients in the emergency department in China. Anticoagulant therapy is needed to prevent clotting in the extracorporeal circulation during CRRT. Regional citrate anticoagulation (RCA) has been shown to potentially be safer and more effective and is now recommended as the preferred anticoagulant method for CRRT. However, there is still a lack of unified standards for RCA management in the world, and there are many problems in using this method in clinical practice. The Emergency Medical Doctor Branch of the Chinese Medical Doctor Association (CMDA) organized a panel of domestic emergency medicine experts and international experts of CRRT to discuss RCA-related issues, including the advantages and disadvantages of RCA in CRRT anticoagulation, the principle of RCA, parameter settings for RCA, monitoring of RCA (mainly metabolic acid–base disorders), and special issues during RCA. Based on the latest available research evidence as well as the paneled experts’ clinical experience, considering the generalizability, suitability, and potential resource utilization, while also balancing clinical advantages and disadvantages, a total of 16 guideline recommendations were formed from the experts’ consensus.
Publisher
Springer Science and Business Media LLC
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