Author:
Rathod Ravsaheb H.,Chaudhari Suraj R.,Patil Amod S.,Shirkhedkar Atul A.
Abstract
Abstract
Background
UHPLC-MS/MS is connected in various research facilities for the qualitative and quantitative investigation of a pharmaceutical substance, pharmaceutical items, and biological specimen.
Main body
The commence review article is an endeavor to offer pervasive awareness around assorted aspects and details about the UHPLC-MS/MS and related techniques with the aim on practice to an estimation of medicinal active agents in the last 10 years. The article also focused on isolation, separation, and characterization of present impurity in drug and biological samples.
Conclusion
Review article compiles a general overview of medicinally important drugs and their analysis with UHPLC-MS/MS. It gives fundamental thought regarding applications of UHPLC-MS/MS for the study on safety limit. The summary of developed UHPLC-MS/MS methods gives a contribution to the future trend and limitations in this area of research.
Publisher
Springer Science and Business Media LLC
Reference181 articles.
1. Walter TH, Andrews RW (2014) Recent innovations in UHPLC columns and instrumentation. Trends Anal Chem 63:14–20.
https://doi.org/10.1016/j.trac.2014.07.016
2. Singh S, Prasad L, Kumar V, Roy S, Patnaik SK (2016) Ultra performance liquid chromatography: high throughput analysis over high performance liquid chromatography. Int J Eng Allied Sci 2:19–25
3. Samatha Y, Srividya A, Ajitha A, Rao VUM (2015) Ultra performance liquid chromatography (UPLC). World J Pharm Pharm Sci 8:356–367
4. Swartz ME (2005) UPLC: an introduction and review. J Liq Chromatogr Relat Technol 28:1253–1263.
https://doi.org/10.1081/JLC-200053046
5. Ht Quantitative Analysis for a drug mixture by LC/MS/MS: UPLC-MS/MS and HPLC-MS/MS Compared (2005) water.
http://www.water.com
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