Recommendations for the optimal introduction of novel antibiotics to treat uncomplicated gonorrhoea in the face of increasing antimicrobial resistance: a case study with zoliflodacin

Author:

Pascual Fernando,Au Carmen,Chikwari Chido Dziva,Daram Pierre,Deal Carolyn,Miranda Angelica Espinosa,Grad Yonatan H.,Hook Edward WIII,Kittiyaowamarn Rossaphorn,Luckey Alison,Low Nicola,Maseko Venessa,Peters Remco P. H.,Roberts Teri,Unemo Magnus,Srinivasan Subasree

Funder

Governments of Germany, the Netherlands and the United Kingdom

Publisher

Springer Science and Business Media LLC

Reference17 articles.

1. World Health Organization. Gonorrhoea (Neisseria gonorrhoeae infection). https://www.who.int/news-room/fact-sheets/detail/gonorrhoea-(neisseria-gonorrhoeae-infection. Accessed 25 Sept 2023.

2. Global progress report on HIV, viral hepatitis and sexually transmitted infections, 2021. Accountability for the global health sector strategies 2016–2021: actions for impact. Geneva: World Health Organization; 2021. https://www.who.int/publications/i/item/9789240027077. Accessed 25 Sept 2025.

3. World Health Organization. Fact sheet: Multi-drug resistant gonorrhoea. https://www.who.int/news-room/fact-sheets/detail/multi-drug-resistant-gonorrhoea. Accessed 25 Sept 2023.

4. Unemo M, Lahra MM, Escher M, Eremin S, Cole MJ, Galarza P, Ndowa F, Martin I, Dillon JR, Galas M, Ramon-Pardo P, Weinstock H, Wi T. WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18: a retrospective observational study. Lancet Microbe. 2021;2(11):e627–36.

5. Alirol E, Wi TE, Bala M, Bazzo ML, Chen XS, Deal C, Dillon JR, Kularatne R, Heim J, Hooft van Huijsduijnen R, Hook EW, Lahra MM, Lewis DA, Ndowa F, Shafer WM, Tayler L, Workowski K, Unemo M, Balasegaram M. Multidrug-resistant gonorrhea: a research and development roadmap to discover new medicines. PLoS Med. 2017;14(7):e1002366.

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