Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infection

Author:

Ma LanYing,Ji Lingyun,Wang Tong,Zhai Zhe,Su PeiWei,Zhang YaNan,Wang Yuan,Zhao WenXiao,Wu ZhiChun,Yu HuaYun,Zhao HaiJun

Abstract

AbstractInfluenza A viruses (IAV) are a prevalent respiratory pathogen that can cause seasonal flu and global pandemics, posing a significant global public health threat. Emerging research suggests that IAV infections may disrupt the balance of gut microbiota, while gut dysbiosis can affect disease progression in IAV patients. Therefore, restoring gut microbiota balance may represent a promising therapeutic target for IAV infections. Traditional Chinese medicine, with its ability to regulate gut microbiota, offers significant potential in preventing and treating IAV. This article provides a comprehensive review of the relationship between IAV and gut microbiota, highlighting the impact of gut microbiota on IAV infections. It also explores the mechanisms and role of traditional Chinese medicine in regulating gut microbiota for the prevention and treatment of IAV, presenting novel research avenues for traditional Chinese medicine-based IAV treatments.

Funder

the Major Basic Program of Natural Science Foundation of Shandong Province

the Shandong Province Universities’ Development Plan for Youth Innovation Teams

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Virology

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