Associations of PGK1 promoter hypomethylation and PGK1-mediated PDHK1 phosphorylation with cancer stage and prognosis: a TCGA pan-cancer analysis

Author:

Shao Fei123,Yang Xueying1,Wang Wei1,Wang Juhong1,Guo Wei1,Feng Xiaoli4,Shi Susheng4,Xue Qi15,Gao Shugeng15,Gao Yibo1,Lu Zhimin35,He Jie15ORCID

Affiliation:

1. Department of Thoracic Surgery; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; No.17 Panjiayuannanli, Chaoyang District Beijing 100021 P. R. China

2. Qingdao Cancer Institute; Cancer Institute of The Affiliated Hospital of Qingdao University; Qingdao 266003 Shandong P. R. China

3. Zhejiang Provincial Key Laboratory of Pancreatic Disease; The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine; Hangzhou 310029 Zhejiang P. R. China

4. Department of Pathology; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Beijing 100021 P. R. China

5. State Key Laboratory of Molecular Oncology; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Beijing 100021 P. R. China

Funder

National Basic Research Program of China

Beijing Municipal Science and Technology Commission

CAMS Initiative for Innovative Medicine

Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences

Beijing Municipal Science & Technology Commission

The National Key R&D Program of China

Publisher

Wiley

Subject

Cancer Research,Oncology

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