Abstract
Abstract
Background
To investigate the application effect of artificial intelligence (AI)-based fundus screening system in real-world clinical environment.
Methods
A total of 637 color fundus images were included in the analysis of the application of the AI-based fundus screening system in the clinical environment and 20,355 images were analyzed in the population screening.
Results
The AI-based fundus screening system demonstrated superior diagnostic effectiveness for diabetic retinopathy (DR), retinal vein occlusion (RVO) and pathological myopia (PM) according to gold standard referral. The sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of three fundus abnormalities were greater (all > 80%) than those for age-related macular degeneration (ARMD), referable glaucoma and other abnormalities. The percentages of different diagnostic conditions were similar in both the clinical environment and the population screening.
Conclusions
In a real-world setting, our AI-based fundus screening system could detect 7 conditions, with better performance for DR, RVO and PM. Testing in the clinical environment and through population screening demonstrated the clinical utility of our AI-based fundus screening system in the early detection of ocular fundus abnormalities and the prevention of blindness.
Funder
Natural Science Foundation of Xinjiang Uygur Autonomous Region
Xinjiang Uygur Autonomous Region Innovation Environment (Talents, Bases) Special Project
The Pearl River Scholar Tianshan Talent Cooperation’s Expert Studio Innovation Team
Science and Technology Program of Guangzhou
Publisher
Springer Science and Business Media LLC
Subject
Radiology, Nuclear Medicine and imaging,Biomedical Engineering,General Medicine,Biomaterials,Radiological and Ultrasound Technology
Cited by
1 articles.
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