Reducing prescribing of antibiotics for acute respiratory infections using a frontline nurse-led EHR-Integrated clinical decision support tool: protocol for a stepped wedge randomized control trial

Author:

Stevens Elizabeth R.,Agbakoba Ruth,Mann Devin M.,Hess Rachel,Richardson Safiya I.,McGinn Thomas,Smith Paul D.,Halm Wendy,Mundt Marlon P.,Dauber-Decker Katherine L.,Jones Simon A.,Feldthouse Dawn M.,Kim Eun Ji,Feldstein David A.

Abstract

Abstract Background Overprescribing of antibiotics for acute respiratory infections (ARIs) remains a major issue in outpatient settings. Use of clinical prediction rules (CPRs) can reduce inappropriate antibiotic prescribing but they remain underutilized by physicians and advanced practice providers. A registered nurse (RN)-led model of an electronic health record-integrated CPR (iCPR) for low-acuity ARIs may be an effective alternative to address the barriers to a physician-driven model. Methods Following qualitative usability testing, we will conduct a stepped-wedge practice-level cluster randomized controlled trial (RCT) examining the effect of iCPR-guided RN care for low acuity patients with ARI. The primary hypothesis to be tested is: Implementation of RN-led iCPR tools will reduce antibiotic prescribing across diverse primary care settings. Specifically, this study aims to: (1) determine the impact of iCPRs on rapid strep test and chest x-ray ordering and antibiotic prescribing rates when used by RNs; (2) examine resource use patterns and cost-effectiveness of RN visits across diverse clinical settings; (3) determine the impact of iCPR-guided care on patient satisfaction; and (4) ascertain the effect of the intervention on RN and physician burnout. Discussion This study represents an innovative approach to using an iCPR model led by RNs and specifically designed to address inappropriate antibiotic prescribing. This study has the potential to provide guidance on the effectiveness of delegating care of low-acuity patients with ARIs to RNs to increase use of iCPRs and reduce antibiotic overprescribing for ARIs in outpatient settings. Trial registration ClinicalTrials.gov Identifier: NCT04255303, Registered February 5 2020, https://clinicaltrials.gov/ct2/show/NCT04255303.

Funder

National Institute of Allergy and Infectious Diseases

Publisher

Springer Science and Business Media LLC

Subject

Health Informatics,Health Policy,Computer Science Applications

Reference51 articles.

1. Centers for Disease Control and Prevention. Antibiotic Use in the United States, 2021 Update: Progress and Opportunities 2021 [Available from: https://www.cdc.gov/antibiotic-use/pdfs/stewardship-report-2021-H.pdf.

2. Duffy E, Ritchie S, Metcalfe S, Van Bakel B, Thomas MG. Antibacterials dispensed in the community comprise 85%-95% of total human antibacterial consumption. J Clin Pharm Ther. 2018;43(1):59–64.

3. Public Health Agency of Sweden, National Veterinary Institute. Swedres-Svarm: Consumption of antibiotics and occurrence of antibiotic resistance in Sweden: Solna, Sweden; 2018 [Available from: https://www.sva.se/media/jzdlctnk/rapport_swedres-svarm_2018.pdf.

4. Hopkins S, Muller-Pebody B, Guy R, Gerver S, Ironmonger D, Puleston R et al. English surveillance programme for antimicrobial utilisation and resistance (ESPAUR) 2010 to 2014: report 20152015.

5. Fleming-Dutra KE, Hersh AL, Shapiro DJ, Bartoces M, Enns EA, File TM Jr, et al. Prevalence of Inappropriate Antibiotic prescriptions among US Ambulatory Care visits, 2010–2011. JAMA. 2016;315(17):1864–73.

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