Abstract
AbstractSeveral flavonoids have been recognized as nutraceuticals, and myricetin is a good example. Myricetin is commonly found in plants and their antimicrobial and antioxidant activities is well demonstrated. One of its beneficial biological effects is the neuroprotective activity, showing preclinical activities on Alzheimer, Parkinson, and Huntington diseases, and even in amyotrophic lateral sclerosis. Also, myricetin has revealed other biological activities, among them as antidiabetic, anticancer, immunomodulatory, cardiovascular, analgesic and antihypertensive. However, few clinical trials have been performed using myricetin as nutraceutical. Thus, this review provides new insights on myricetin preclinical pharmacological activities, and role in selected clinical trials.
Publisher
Springer Science and Business Media LLC
Subject
Complementary and alternative medicine
Reference161 articles.
1. Matilla MA. Chapter 10 - metabolic responses of plants upon different plant–pathogen interactions. In: Ahmad P, Ahanger MA, Singh VP, Tripathi DK, Alam P, Alyemeni MN, editors. Plant metabolites and regulation under environmental stress. Cambridge: Academic Press; 2018. p. 195–214.
2. Imran M, Salehi B, Sharifi-Rad J, Gondal TA, Saeed F, Imran A, Shahbaz M, Fokou PVT, Arshad MU, Khan H, et al. Kaempferol: a key emphasis to its anticancer potential. Molecules. 2019;24(12):2277.
3. Sharifi-Rad J, Sharifi-Rad M, Salehi B, Iriti M, Roointan A, Mnayer D, Soltani-Nejad A, Afshari A. In vitro and in vivo assessment of free radical scavenging and antioxidant activities of Veronica persica Poir. Cell Mol Biol. 2018;64(8):57–64.
4. Rauter AP, Ennis M, Hellwich K-H, Herold BJ, Horton D, Moss GP, Schomburg I. Nomenclature of flavonoids (IUPAC Recommendations 2017). Pure Appl Chem. 2018;90(9):1429.
5. Yao Y, Lin G, Xie Y, Ma P, Li G, Meng Q, Wu T. Preformulation studies of myricetin: a natural antioxidant flavonoid. Pharmazie. 2014;69(1):19–26.
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