Author:
Xia Feifei,Guo Foqing,Liu Zhe,Zeng Jie,Ma Xuehua,Yu Chongqing,Li Changxue
Abstract
Abstract
Objective
This study sought to evaluate the worth of the general characteristics of enhanced CT images and the histogram parameters of each stage in distinguishing pleomorphic adenoma (PA) and adenolymphoma (AL).
Methods
The imaging features and histogram parameters of preoperative enhanced CT images in 20 patients with PA and 29 patients with AL were analyzed. Tumor morphology and histogram parameters of PA and AL were compared. Area under the curve (AUC), sensitivity, and subject operational feature specificity (ROC) analysis were used to determine the differential diagnostic effect of single-stage or multi-stage parameter combinations.
Results
The difference in CT value and net enhancement value of arterial phase (AP) were significant (p < 0.05); Flat sweep phase (FSP), AP mean, percentiles, 10th, 50th, 90th, 99th and arterial period variance and venous phase (VP) kurtosis in the nine histogram parameters of each period (p < 0.05). An analysis of the ROC curve revealed a maximum area beneath the curve (AUC) in the 90th percentile of FSP for a single-parameter differential diagnosis to be 0.870. The diagnostic efficacy of the mean value of FSP + The 90th percentile of AP + Kurtosis of VP was the best in multi-parameter combination diagnosis, with an AUC of 0.925, and the sensitivity and specificity of 0.900 and 0.850, respectively.
Conclusion
The histogram analysis of enhanced CT images is valuable for the differentiation of PA and AL. Moreover, the combination of single-stage parameters or multi-stage parameters can improve the differential diagnosis efficiency.
Publisher
Springer Science and Business Media LLC
Subject
Radiology, Nuclear Medicine and imaging
Reference32 articles.
1. Thielker J, Grosheva M, Ihrler S, Wittig A, Guntinas-Lichius O. Contemporary Management of Benign and malignant parotid tumors. Front Surg. 2018;5:39.
2. Larian B. Parotidectomy for Benign Parotid tumors. Otolaryngol Clin North Am. 2016;49(2):395–413.
3. Shao S, Mao N, Liu W, Cui J, Xue X, Cheng J, Zheng N, Wang B. Epithelial salivary gland tumors: utility of radiomics analysis based on diffusion-weighted imaging for differentiation of benign from malignant tumors. J Xray Sci Technol. 2020;28(4):799–808.
4. Espinoza S, Felter A, Malinvaud D, Badoual C, Chatellier G, Siauve N, Halimi P. Warthin’s Tumor of parotid gland: Surgery or follow-up? Diagnostic value of a decisional algorithm with functional MRI. Diagn Interv Imaging. 2016;97(1):37–43.
5. Liu Y, Zheng J, Lu X, Wang Y, Meng F, Zhao J, Guo C, Yu L, Zhu Z, Zhang T. Radiomics-based comparison of MRI and CT for differentiating pleomorphic adenomas and Warthin tumors of the parotid gland: a retrospective study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021;131(5):591–9.