MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial

Author:

Fransen Puck SS,Beumer Debbie,Berkhemer Olvert A,van den Berg Lucie A,Lingsma Hester,van der Lugt Aad,van Zwam Wim H,van Oostenbrugge Robert J,Roos Yvo BWEM,Majoie Charles B,Dippel Diederik WJ,

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Medicine (miscellaneous)

Reference47 articles.

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2. Hacke W, Kaste M, Bluhmki E, Brozman M, Davalos A, Guidetti D, Larrue V, Lees KR, Medeghri Z, Machnig T, Schneider D, Von Kummer R, Wahlgren N, Toni D, ECASS Investigators: Thrombolysis with Alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med. 2008, 359: 1317-1329. 10.1056/NEJMoa0804656.

3. Lees KR, Bluhmki E, Von Kummer R, Brott TG, Toni D, Grotta JC, Albers GW, Kaste M, Marler JR, Hamilton SA, Tilley BC, Davis SM, Donnan GA, Hacke W, Allen K, Mau J, Meier D, Del Zoppo G, De Silva DA, Butcher KS, Parsons MW, Barber PA, Levi C, Bladin C, Byrnes G, ECASS, Atlantis NINDS, Group, Epithet rt-PA Study: Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010, 375: 1695-1703. 10.1016/S0140-6736(10)60491-6.

4. Beumer DSG, Fonvile S, Van Oostenbrugge RJ, Homburg PJ, Van der Lugt A, Dippel DWJ: Intra-arterial occlusion in acute ischemic stroke: relative frequency in an unselected population. Cerebrovasc Dis. 2013, 35 (S33): 66-

5. Derex L, Nighoghossian N, Hermier M, Adeleine P, Froment JC, Trouillas P: Early detection of cerebral arterial occlusion on magnetic resonance angiography: predictive value of the baseline NIHSS score and impact on neurological outcome. Cerebrovasc Dis. 2002, 13: 225-229. 10.1159/000057847.

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