Author:
Chen Xinyue,Yu Wenlu,Zhang Jing,Fan Xiao,Liu Xiao,Liu Qi,Pan Su,Dixon Richard A. F.,Li Pengyang,Yu Peng,Shi Ao
Abstract
AbstractIschemic vascular disease is a major healthcare problem. The keys to treatment lie in vascular regeneration and restoration of perfusion. However, current treatments cannot satisfy the need for vascular regeneration to restore blood circulation. As biomedical research has evolved rapidly, a variety of potential alternative therapeutics has been explored widely, such as growth factor-based therapy, cell-based therapy, and material-based therapy including nanomedicine and biomaterials. This review will comprehensively describe the main pathogenesis of vascular injury in ischemic vascular disease, the therapeutic function of the above three treatment strategies, the corresponding potential challenges, and future research directions.
Funder
Natural Science Foundation in Jiangxi Province
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology,Biomedical Engineering,Environmental Engineering
Cited by
2 articles.
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