Artificial genetic polymers against human pathologies-Reference-Cited by-同舟云学术

Artificial genetic polymers against human pathologies

Published:2022-12-06 Issue:1 Volume:17 Page:
ISSN:1745-6150
Container-title:Biology Direct
language:en
Short-container-title:Biol Direct

Author:

Ivanov Gleb S.,Tribulovich Vyacheslav G.,Pestov Nikolay B.,David Temitope I.,Amoah Abdul-Saleem,Korneenko Tatyana V.,Barlev Nikolai A.

Abstract

AbstractOriginally discovered by Nielsen in 1991, peptide nucleic acids and other artificial genetic polymers have gained a lot of interest from the scientific community. Due to their unique biophysical features these artificial hybrid polymers are now being employed in various areas of theranostics (therapy and diagnostics). The current review provides an overview of their structure, principles of rational design, and biophysical features as well as highlights the areas of their successful implementation in biology and biomedicine. Finally, the review discusses the areas of improvement that would allow their use as a new class of therapeutics in the future.

Publisher

Springer Science and Business Media LLC

Subject

Applied Mathematics,General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology,Modeling and Simulation,Ecology, Evolution, Behavior and Systematics,Immunology

Link

https://link.springer.com/content/pdf/10.1186/s13062-022-00353-7.pdf

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