Author:
Liu Mengyun,He Hengqian,Zhang Juntao,Xin Shuanghua,Lu Qinkang,Zhang Lifang,Ren Weina
Abstract
Abstract
Background
To report a case of retinitis with multiple intraocular viral infections after second haematopoietic stem cell transplantation.
Case presentation
A 39-year-old female patient developed retinitis after a second haematopoietic stem cell transplant. Right eye was tested for three viral infections– cytomegalovirus, Epstein‒Barr virus and herpes simplex virus, while left was infected with cytomegalovirus. The patient was subsequently treated with vitreous cavity ganciclovir injections, and 1 week later both eyes tested negative for aqueous humour viruses.
Discussion and conclusion
CMV, EBV and HSV belong to the herpes virus family. They are all commonly observed in the body and represent opportunity infectious viruses. The retinitis they cause have different characteristics. But simultaneous infection of the eye by multiple viruses is quite rare. In this case, three viruses were detected in the patient’s eye, but whether the retina was caused by all three viruses at the same time could not be determined. A satisfactory outcome was achieved after treatment with vitreous cavity ganciclovir injection.
Funder
Science and Technology Program of Traditional Chinese Medicine in Zhejiang Province
Zhejiang Medical and Health Science and Technology Plan Project
Science and Technology Innovation 2025 Major Project of Ningbo
Ningbo Clinical Research Center for Ophthalmology and the Project of NINGBO Leading Medical&Health Disipline
Ningbo Clinical Research Center for Ophthalmology
Ningbo Key Laboratory for neuroretinopathy medical research
Ningbo Public Welfare Science and Technology Plan Project
Ningbo Natural Science Foundation
Zhejiang Provincial Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Ophthalmology,General Medicine