Author:
Dai Xianmin,Feng Jiayi,Chen Yi,Huang Si,Shi Xiaofei,Liu Xia,Sun Yang
Abstract
AbstractNonalcoholic fatty liver disease (NAFLD) has become the world's largest chronic liver disease, while there is still no specific drug to treat NAFLD. Traditional Chinese Medicine (TCM) have been widely used in hepatic diseases for centuries in Asia, and TCM’s holistic concept and differentiation treatment of NAFLD show their advantages in the treatment of this complex metabolic disease. However, the multi-compounds and multi-targets are big obstacle for the study of TCM. Here, we summarize the pharmacological actions of active ingredients from frequently used single herbs in TCM compounds. The combined mechanism of herbs in TCM compounds are further discussed to explore their comprehensive effects on NAFLD. This article aims to summarize multiple functions and find the common ground for TCM treatment on NAFLD, thus providing enrichment to the scientific connotation of TCM theories and promotes the exploration of TCM therapies on NAFLD.
Funder
National Natural Science Foundation of China
Collaborative Innovation Center for Water Treatment Technology and Materials
Publisher
Springer Science and Business Media LLC
Subject
Complementary and alternative medicine,Pharmacology