Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration-Reference-Cited by-同舟云学术

Oral administration of the cannabigerol derivative VCE-003.2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-induced neurodegeneration

Published:2019-03-08 Issue:1 Volume:8 Page:
ISSN:2047-9158
Container-title:Translational Neurodegeneration
language:en
Short-container-title:Transl Neurodegener

Author:

Aguareles José,Paraíso-Luna Juan,Palomares Belén,Bajo-Grañeras Raquel,Navarrete Carmen,Ruiz-Calvo Andrea,García-Rincón Daniel,García-Taboada Elena,Guzmán Manuel,Muñoz Eduardo,Galve-Roperh Ismael^ORCID

Funder

Ministerio de Economía, Industria y Competitividad, Gobierno de España

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Cognitive Neuroscience,Clinical Neurology

Link

http://link.springer.com/content/pdf/10.1186/s40035-019-0148-x.pdf

Reference43 articles.

1. Ross CA, Aylward EH, Wild EJ, Langbehn DR, Long JD, Warner JH, Scahill RI, Leavitt BR, Stout JC, Paulsen JS, Reilmann R, Unschuld PG, Wexler A, Margolis RL, Tabrizi SJ. Huntington disease: Natural history, biomarkers and prospects for therapeutics. Nat Rev Neurol. 2014;10:204–16.

2. Conforti P, Besusso D, Bocchi VD, Faedo A, Cesana E, Rossetti G, Ranzani V, Svendsen CN, Thompson LM, Toselli M, Biella G, Pagani M, Cattaneo E. Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes. Proc Natl Acad Sci U S A. 2018;115:E762–71.

3. Lim RG, Salazar LL, Wilton DK, King AR, Stocksdale JT, Sharifabad D, Lau AL, Stevens B, Reidling JC, Winokur ST, Casale MS, Thompson LM, Pardo M, AGG D-B, Straccia M, Sanders P, Alberch J, Canals JM, Kaye JA, Dunlap M, Jo L, May H, Mount E, Anderson-Bergman C, Haston K, Finkbeiner S, Kedaigle AJ, Gipson TA, Yildirim F, Ng CW, Milani P, Housman DE, Fraenkel E, Allen ND, Kemp PJ, Atwal RS, Biagioli M, Gusella JF, ME MD, Akimov SS, Arbez N, Stewart J, Ross CA, Mattis VB, Tom CM, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Svendsen CN. Developmental alterations in Huntington’s disease neural cells and pharmacological rescue in cells and mice. Nat Neurosci. 2017;20:648–60.